BACKGROUND: Facial aging is a complex and multifactorial process that progressively affects the structure, volume, and quality of facial tissues. This study aims to present a case series involving South American patients of different generations and facial morphotypes treated with HArmonyCa®, a hybrid filler composed of hyaluronic acid and calcium hydroxylapatite.
METHODS: Four patients of varying ages, genders, and facial profiles underwent individualized treatment plans tailored to their aesthetic concerns and aging patterns. All patients received clinical evaluation and three-dimensional imaging analysis using the Vectra 3D system, which enabled precise quantitative assessment of outcomes.
RESULTS: Significant improvement in facial firmness and contour definition was observed, yielding a rejuvenated, natural-looking appearance. The bio-stimulatory effects of calcium hydroxylapatite, combined with the immediate volumization from hyaluronic acid, produced a noticeable and progressive lifting effect. Three-dimensional imaging supported the clinical findings by demonstrating tissue repositioning and volumetric enhancement in strategic facial areas.
CONCLUSION: This case series highlights the potential of HArmonyCa® as an effective, safe, and versatile approach for facial rejuvenation, adaptable to a wide range of patient profiles. The integration of objective tools such as 3D imaging further enhances treatment planning and outcome evaluation.
LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
Clinical Outcomes of HArmonyCa® in South American Patients: A Case Series Using Vectra 3D Technology.
TL;DR
BACKGROUND: Facial aging is a complex and multifactorial process that progressively affects the structure, volume, and quality of facial tissues. This study aims to present a case series involving South American patients of different generations and facial morphotypes treated with HArmonyCa®, a hybrid filler composed of hyaluronic acid and calcium hydroxylapatite. METHODS: Four patients of varying ages, genders, and facial profiles underwent individualized treatment plans tailored to their aesth
Credibility Assessment
Preliminary — 38/100
Study Design
Rigor of the research methodology
5/20
Sample Size
Whether the study was sufficiently powered
7/20
Peer Review
Review status and journal reputation
10/20
Replication
Has this finding been independently reproduced?
6/20
Transparency
Funding disclosure and data availability
10/20
Overall
Sum of all five dimensions
38/100
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