How We Score
How we vet the research — transparency first
Promising
Blood Pressure Changes May Signal Cognitive and Functional Decline in the Very Elderly
This study suggests that unexpected changes in blood pressure in people aged 85+ may warn of upcoming cognitive or functional decline, but the finding is preliminary and based on a …
51
/100
Novel statistical method (DTW) applied in this context without validation against standard methods or external replication; effect sizes not clearly …
Promising
How the brain's energy pathways change across regions and lifespan
This paper creates detailed maps of how the brain's energy-producing systems are organized and how they change from birth through adulthood—valuable context for understanding brain aging, but not yet evidence …
53
/100
Very recent publication (Jan 2026) with zero citations—no independent replication or community scrutiny yet. Gene expression proxies for metabolic flux …
Promising
Mitochondrial Transplantation Restores Muscle Function
Promising results but more studies needed.
61
/100
Promising
Telomere Extension via AAV Gene Therapy in Primates
Promising results but more studies needed.
62
/100
Promising
Epigenetic Clock Reversal Achieved with Lifestyle Intervention
Promising results but more studies needed.
57
/100
74
/100